Young patient receives HD therapy sitting in a chair with a clinician beside her

Polyflux H Dialyzer Series

Vantive Polyflux dialyzer offered in a high-flux series — Polyflux H. Both series promote biocompatibility and deliver proven performance.


Polyflux H: For effective convective therapies and regular high-flux HD

The Polyflux H Dialyzer series is a range of dialyzers that effectively support the delivery of high-volume convective therapies1 (HDF or HF mode), as well as regular high-flux hemodialysis. With over 300 million Polyflux H dialyzers having performed high-quality treatment around the world since 1988,2 the series is proven to deliver biocompatibility3 and endotoxin retention4 with consistent performance. The series helps control the loss of essential proteins such as albumin,5 which is particularly challenging at high flows and transmembrane pressures. Polyflux H dialyzers are aimed at delivering stable and high-performing convective treatments, supporting a consistent reach of high volumes of substitution fluid.

Polyflux H Dialyzers

Benefits of the Polyflux H Dialyzer series

#1

Promoting biocompatibility3,4 with convective volumes in mind

#2

3-layer Polyamix membrane has been designed to optimize the combination of high diffusive and convective transport rates

#3

Narrow pore size allows for effective permeability to small and conventional middle molecules1

#4

Steam sterilized from the inside-out, promoting biocompatibility and preventing exposure to manufacturing residues and dangerous chemicals6,7

Learn more about the Polyflux H dialyzer series

Read more about how the Polyflux H Dialyzer series contributes to Vantive’s larger dialyzer portfolio by providing safe, effective  and biocompatible convective therapies to patients.


Benefits of the Polyflux L Dialyzer series

#1

Promoting biocompatibility4,6 with high performance in mind

#2

Distinctive membrane design that prevents endotoxins from crossing the dialyzer membrane3,4

#3

Steam sterilized inside-out, preventing exposure to chemicals such as ethylene oxide and manufacturing residues6,7

#4

Exclusive 3-layered membrane structure, designed to support a stable high performance over time8

Learn more about the Polyflux L Dialyzer series

Read more about how the Polyflux L Dialyzer series contributes to Vantive’s larger dialyzer portfolio by providing biocompatible, yet effective low-flux therapies to patients.


Important Safety Information 

Indications/Intended Use: Polyflux 6 H is intended for chronic and acute applications in hemodialysis, hemodiafiltration and hemofiltration on small patients including pediatric indications, considering blood flow, body weight and extracorporeal blood volume. 

For safe and proper use of the device, please refer to the Instructions for Use.

Vantive, Artis Physio, Polyamix, Polyflux and Revaclear are trademarks of Vantive Health LLC or its affiliates.

References
  1. Maduell F, Moreso F, Pons M, et al. High-efficiency postdilution online hemodiafiltration reduces all-cause mortality in hemodialysis patients [published correction appears in J Am Soc Nephrol. 2014 May;25(5):1130]. J Am Soc Nephrol. 2013;24(3):487-497. 

  2. Vantive Health LLC. Sales data, 2018. Data on file.

  3. Schepers E, Glorieux G, Eloot S, et al. Assessment of the association between increasing membrane pore size and endotoxin permeability using a novel experimental dialysis simulation set-up. BMC Nephrol. 2018;19(1):1.

  4. Ronco C, Crepaldi C, Brendolan A, et al. Evolution of synthetic membranes for blood purification: the case of the Polyflux family. Nephrol Dial Transplant. 2003;18 Suppl 7:vii10-vii55.

  5. Potier J, Queffeulou G, Bouet J. Are all dialyzers compatible with the convective volumes suggested for postdilution online hemodiafiltration?. Int J Artif Organs. 2016;39(9):460-470.

  6. Golli-Bennour EE, Kouidhi B, Dey M, et al. Cytotoxic effects exerted by polyarylsulfone dialyser membranes depend on different sterilization processes. Int Urol Nephrol. 2011;43(2):483-490. 

  7. Purello D'Ambrosio F, Savica V, Gangemi S, et al. Ethylene oxide allergy in dialysis patients. Nephrol Dial Transplant. 1997;12(7):1461-1463. 

  8. Vantive Health LLC. Polyflux L Instructions for Use. 2009; N50 403; version 010. Data on file.