A healthcare professional holds a Theranova dialyzer by a AK 98 machine

An Innovative Class of Dialyzer Membrane Technology

As the hemodialyzer with expanded solute removal profile, Theranova dialyzer and its MCO membrane enable HDx therapy to provide expanded hemodialysis.1

HDx therapy - one step closer to the natural kidney

HDx therapy uniquely enabled by the first-of-its-kind Theranova Dialyzer provides expanded hemodialysis therapy, thanks to the technology of its MCO membrane, bringing expanded hemodialysis filtration one step closer to the natural kidney2 by removing large-middle molecule uremic toxins linked to cardiovascular disease, inflammation and other dialysis-related comorbidities.3

Female patient receiving HDx therapy in a hospital

Improving outcomes with no additional requirements

By simply changing high-flux hemodialysis to HDx therapy enabled by Theranova dialyzer with the MCO membrane, diffusion and convection are conveniently combined inside the hollow fiber dialyzer to perform HDx therapy, with no special requirement of a particular hardware, preparation of replacement fluid, or additional nursing skill, beyond what is necessary to perform traditional hemodialysis in standard mode.4

Medical professional providing HDx therapy to a woman in a hospital setting
An HD patient undergoing hemodialysis with the AK 98 dialysis system and Revaclear dialyzer

More about Theranova Dialyzer

Discover more about how Theranova dialyzer works, the evidence that supports its use and available resources for additional information.

Learn more

Renal care resources to support clinicians

We offer numerous resources that provide detailed information on using our AK 98 dialysis system, which can deliver HDx therapy using Theranova dialyzer, and on our support services for both clinicians and patients.

View resources

Important Safety Information

Indications for Use: THERANOVA dialyzers are indicated for treatment of chronic and acute renal failure by Hemodialysis

Caution: Do not use THERANOVA dialyzers for HDF (hemodiafiltration) or HF (hemofiltration) due to higher permeability of larger molecular weight proteins such as albumin.

For safe and proper use of the device, please refer to the Instructions for Use.

 

Vantive, AK 98, HDx, MCO and Theranova are trademarks of Vantive Health LLC or its affiliates.

References

  1. Device Classification Under Section 513(f)(2)(DeNovo). Accessdata.fda.gov. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfpmn/denovo.cfm?id=DEN190042. Published 2020.

  2. Zweigart C, Boschetti-de-Fierro A, Hulko M, et al. Medium cut-off membranes — closer to the natural kidney removal function. Int J Artif Organs. 2017;40(7):328-334.

  3. Ronco C, La Manna G. Expanded hemodialysis: a new therapy for a new class of membranes. Contrib Nephrol. 2017;190:124-133.

  4. Ronco C. The rise of expanded hemodialysis. Blood Purif. 2017;44(2):I-VIII.